WHO Antibiotics Portal

Amikacin

Antibiotic

Amikacin
ACCESS group

Indications

First choice
cefotaxime Acute pyelonephritis (severe) ceftriaxone Acute pyelonephritis (severe)

Second choice
cloxacillin Sepsis without septic shock
Amoxicillin

Antibiotic

Amoxicillin
ACCESS group

Indications

First choice
Chronic obstructive pulmonary disease with acute exacerbation gentamicin Sepsis without septic shock
Amoxicillin + clavulanic acid

Antibiotic

Amoxicillin + clavulanic acid
ACCESS group

Indications

First choice
Infectious cystitis Chronic obstructive pulmonary disease with acute exacerbation
Ampicillin

Antibiotic

Ampicillin
ACCESS group

Indications

First choice
gentamicin Peritoneal abscess (severe) gentamicin Sepsis without septic shock gentamicin Peritoneal abscess (mild-moderate) gentamicin Peritonitis (severe) gentamicin Acute malnutrition in infants, children or adolescents (complicated) [children] gentamicin Peritonitis (mild-moderate) gentamicin Bacterial pneumonia (Community-acquired pneumonia - severe) [children]

Second choice
Bacterial meningitis
Azithromycin

Antibiotic

Azithromycin
WATCH group

Indications

First choice
ceftriaxone Gonococcal infection

Second choice
cefixime Gonococcal infection
Aztreonam

Antibiotic

Aztreonam
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Other specified bacterial diseases
Benzathine benzylpenicillin

Antibiotic

Benzathine benzylpenicillin
ACCESS group

Indications

First choice
Syphilis Congenital syphilis [children]
Benzylpenicillin

Antibiotic

Benzylpenicillin
ACCESS group

Indications

First choice
Syphilis Congenital syphilis [children] gentamicin Sepsis without septic shock gentamicin Acute malnutrition in infants, children or adolescents (complicated) [children] gentamicin Bacterial pneumonia (Community-acquired pneumonia - severe) [children]

Second choice
Bacterial meningitis
Capreomycin

Antibiotic

Capreomycin
ACCESS group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Multi-drug resistant Mycobacterium tuberculosis
Cefalexin

Antibiotic

Cefalexin
ACCESS group

Indications

Second choice
Chronic obstructive pulmonary disease with acute exacerbation
Cefazolin

Antibiotic

Cefazolin
ACCESS group

Indications

First choice
Other specified prophylactic measures metronidazole Other specified prophylactic measures

Second choice
Osteomyelitis or osteitis Bacterial infection of joint
Cefepime

Antibiotic

Cefepime
WATCH group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Other specified bacterial diseases
Cefixime

Antibiotic

Cefixime
WATCH group

Indications

Second choice
Infectious gastroenteritis or colitis without specification of infectious agent azithromycin Gonococcal infection
Cefotaxime

Antibiotic

Cefotaxime
WATCH group

Indications

Bacterial infection of unspecified site
Ceftaroline

Antibiotic

Ceftaroline
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Other specified bacterial diseases
Ceftazidime

Antibiotic

Ceftazidime
WATCH group

Indications

First choice
vancomycin Endophthalmitis
Ceftazidime + avibactam

Antibiotic

Ceftazidime + avibactam
RESERVE group

Indications

Carbapenem-resistant Pseudomonas aeruginosa Carbapenem resistant Enterobacterales
Ceftolozane + tazobactam

Antibiotic

Ceftolozane + tazobactam
RESERVE group

Indications

Carbapenem-resistant Pseudomonas aeruginosa
Ceftriaxone

Antibiotic

Ceftriaxone
WATCH group

Indications

First choice
metronidazole Necrotising fasciitis
Cefuroxime

Antibiotic

Cefuroxime
WATCH group

Indications

Second choice
Other specified prophylactic measures
Chloramphenicol

Antibiotic

Chloramphenicol
ACCESS group

Indications

Bacterial infection of unspecified site
Ciprofloxacin

Antibiotic

Ciprofloxacin
WATCH group

Indications

First choice
Inflammatory and other diseases of prostate (mild to moderate)
Clindamycin

Antibiotic

Clindamycin
ACCESS group

Indications

Bacterial infection of unspecified site
Cloxacillin

Antibiotic

Cloxacillin
ACCESS group

Indications

Bacterial infection of unspecified site
Colistin (injection)

Antibiotic

Colistin (injection)
RESERVE group

Indications

Other specified bacterial diseases
Daptomycin

Antibiotic

Daptomycin
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Other specified bacterial diseases
Delafloxacin

Antibiotic

Delafloxacin
WATCH group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Methicillin resistant Staphylococcus aureus
Doxycycline

Antibiotic

Doxycycline
ACCESS group

Indications

First choice
Chlamydia trachomatis

Second choice
Chronic obstructive pulmonary disease with acute exacerbation
Eravacycline

Antibiotic

Eravacycline
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Carbapenem resistant Enterobacterales
Erythromycin

Antibiotic

Erythromycin
WATCH group

Indications

Bacterial infection of unspecified site Chlamydial conjunctivitis Gonococcal infection of eye
Fosfomycin (injection)

Antibiotic

Fosfomycin (injection)
RESERVE group

Indications

Other specified bacterial diseases Carbapenem resistant Acinetobacter baumannii Carbapenem-resistant Pseudomonas aeruginosa Carbapenem resistant Enterobacterales
Gatifloxacin

Antibiotic

Gatifloxacin
WATCH group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Multi-drug resistant Mycobacterium tuberculosis
Gentamicin

Antibiotic

Gentamicin
ACCESS group

Indications

First choice
Neonatal meningitis amoxicillin Bacterial pneumonia (Community-acquired pneumonia - severe) [children] amoxicillin Sepsis without septic shock ampicillin Acute malnutrition in infants, children or adolescents (complicated) [children] ampicillin Peritonitis (mild-moderate) ampicillin Peritonitis (severe) ampicillin Peritoneal abscess (severe) ampicillin Sepsis without septic shock ampicillin Bacterial pneumonia (Community-acquired pneumonia - severe) [children] ampicillin Peritoneal abscess (mild-moderate) benzylpenicillin Acute malnutrition in infants, children or adolescents (complicated) [children] benzylpenicillin Sepsis without septic shock benzylpenicillin Bacterial pneumonia (Community-acquired pneumonia - severe) [children]

Second choice
Other specified prophylactic measures Gonococcal infection
Imipenem + cilastatin

Antibiotic

Imipenem + cilastatin
WATCH group

Indications

Pseudomonas aeruginosa resistant to other antibiotic Antibiotic resistant Acinetobacter baumannii
Imipenem + cilastatin + relebactam

Antibiotic

Imipenem + cilastatin + relebactam
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Other specified other antibiotic resistant Enterobacterales Carbapenem resistant Enterobacterales Carbapenem-resistant Pseudomonas aeruginosa
Kanamycin (injection)

Antibiotic

Kanamycin (injection)
WATCH group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Multi-drug resistant Mycobacterium tuberculosis
Levofloxacin

Antibiotic

Levofloxacin
WATCH group

Indications

Multi-drug resistant Mycobacterium tuberculosis
Linezolid

Antibiotic

Linezolid
RESERVE group

Indications

Other specified bacterial diseases Multi-drug resistant Mycobacterium tuberculosis
Meropenem

Antibiotic

Meropenem
WATCH group

Indications

Second choice
Neutropenia (high-risk) Peritoneal abscess (severe) Peritonitis (severe) Neonatal meningitis
Meropenem + vaborbactam

Antibiotic

Meropenem + vaborbactam
RESERVE group

Indications

Carbapenem resistant Enterobacterales Carbapenem-resistant Pseudomonas aeruginosa Carbapenem resistant Acinetobacter baumannii
Metronidazole

Antibiotic

Metronidazole
ACCESS group

Indications

First choice
cefazolin Other specified prophylactic measures cefotaxime Peritoneal abscess (severe) cefotaxime Peritonitis (mild-moderate) cefotaxime Peritoneal abscess (mild-moderate) cefotaxime Peritonitis (severe) ceftriaxone Peritoneal abscess (severe) ceftriaxone Peritoneal abscess (mild-moderate) ceftriaxone Peritonitis (mild-moderate) ceftriaxone Peritonitis (severe)

Second choice
ciprofloxacin Peritoneal abscess (mild-moderate) ciprofloxacin Peritonitis (mild-moderate)
Moxifloxacin

Antibiotic

Moxifloxacin
WATCH group

Indications

Multi-drug resistant Mycobacterium tuberculosis Tuberculosis
Ofloxacin

Antibiotic

Ofloxacin
WATCH group

Indications

Multi-drug resistant Mycobacterium tuberculosis Other specified conjunctivitis Infectious keratitis
Omadacycline

Antibiotic

Omadacycline
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Methicillin resistant Staphylococcus aureus
Phenoxymethylpenicillin

Antibiotic

Phenoxymethylpenicillin
ACCESS group

Indications

First choice
Acute pharyngitis Periapical abscess without sinus Bacterial pneumonia (Community-acquired pneumonia - mild to moderate)
Piperacillin + tazobactam

Antibiotic

Piperacillin + tazobactam
WATCH group

Indications

First choice
Peritoneal abscess (severe) Other specified pneumonia (Hospital-acquired pneumonia) Neutropenia (high-risk) Peritonitis (severe)
Plazomicin

Antibiotic

Plazomicin
RESERVE group

Indications

Carbapenem-resistant Pseudomonas aeruginosa Carbapenem resistant Enterobacterales Carbapenem resistant Acinetobacter baumannii
Procaine benzylpenicillin

Antibiotic

Procaine benzylpenicillin
ACCESS group

Indications

First choice
Congenital syphilis [children]

Second choice
Syphilis
Rifabutin

Antibiotic

Rifabutin
WATCH group

Indications

Tuberculosis
Rifampicin

Antibiotic

Rifampicin
WATCH group

Indications

Tuberculosis Other specified tuberculosis Leprosy
Spectinomycin

Antibiotic

Spectinomycin
ACCESS group

Indications

Second choice
Gonococcal infection
Streptomycin (injection)

Antibiotic

Streptomycin (injection)
WATCH group

Indications

Multi-drug resistant Mycobacterium tuberculosis
Sulfadiazine

Antibiotic

Sulfadiazine
ACCESS group

Indications

Toxoplasmosis Bacterial infection of unspecified site
Sulfadimidine

Antibiotic

Sulfadimidine
ACCESS group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Bacterial infection of unspecified site
Sulfamethoxazole + trimethoprim

Antibiotic

Sulfamethoxazole + trimethoprim
ACCESS group

Indications

Bacterial infection of unspecified site Pneumocystosis
Tetracycline

Antibiotic

Tetracycline
ACCESS group

Indications

Bacterial infection of unspecified site Neonatal conjunctivitis or dacryocystitis Other specified conjunctivitis Infectious keratitis Trachoma Infectious blepharitis
Tigecycline

Antibiotic

Tigecycline
RESERVE group

Considered for monitoring purposes. Not listed on Essential Medicines List.

Indications

Other specified bacterial diseases
Trimethoprim

Antibiotic

Trimethoprim
ACCESS group

Indications

First choice
Infectious cystitis
Vancomycin

Antibiotic

Vancomycin
WATCH group

Indications

First choice
ceftazidime Endophthalmitis ceftriaxone Endophthalmitis